Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.37 |
| ▸ | TRPC7 | Q9HCX4 | 1/20 | 0.37 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13270464 | 0.93 | PTGES (0.37) | F10POLBTP53TDP1TLR7 | |
| SCHEMBL13634668 | 0.90 | F10 (0.37) | F10TP53TLR7HSD17B10TRPC3 | |
| SCHEMBL2774000 | 0.86 | POLB (0.49) | POLBTP53TDP1SMN1; SMN2HSD17B10 | |
| SCHEMBL13163171 | 0.83 | F10 (0.36) | F10TP53SMN1; SMN2HSD17B10TRPC3 | |
| SCHEMBL13634788 | 0.82 | S1PR1 (0.48) | POLBTP53TDP1PTPN1 | |
| SCHEMBL13634789 | 0.82 | JAK2 (0.37) | F10IRAK4ABCG2 | |
| SCHEMBL13163173 | 0.81 | GRM2 (0.37) | POLBTP53TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL13634600 | 0.80 | IRAK4 (0.42) | POLBHSD17B10IRAK4LMNAKDM4E | |
| SCHEMBL15888682 | 0.80 | CRHR1 (0.40) | F10SMN1; SMN2HSD17B10TRPC3TRPC7 | |
| SCHEMBL13638928 | 0.79 | S1PR1 (0.48) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |