Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 8/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMO | Q99835 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PAICS | P22234 | 1/20 | 0.35 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634821 | 1.00 | GPR6 (0.44) | GPR6GRM4IRAK4NAMPTPDE10A | |
| SCHEMBL13634671 | 0.88 | PDE10A (0.46) | GPR6IRAK4NAMPTPDE10ASMO | |
| SCHEMBL13634792 | 0.88 | PDE10A (0.46) | GPR6IRAK4NAMPTPDE10ASMO | |
| SCHEMBL13634601 | 0.83 | MCHR1 (0.43) | GPR6IRAK4 | |
| SCHEMBL13634793 | 0.82 | SCD (0.40) | GPR6PAICSCNR1CNR2 | |
| SCHEMBL13634630 | 0.80 | GPR6 (0.40) | GPR6GRM4IRAK4NAMPTSMO | |
| SCHEMBL13634631 | 0.80 | GPR6 (0.40) | GPR6GRM4IRAK4NAMPTSMO | |
| SCHEMBL13634670 | 0.80 | PARP1 (0.38) | GPR6IRAK4PAICSTYK2 | |
| SCHEMBL13638812 | 0.78 | GPR6 (0.39) | GPR6IRAK4PAICSTYK2HPGDS | |
| SCHEMBL13634835 | 0.77 | PIM1 (0.42) | GPR6PDE4BPDE4DPAICSTYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |