Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 5/20 | 0.48 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.37 |
| ▸ | MERTK | Q12866 | 1/20 | 0.37 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.36 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.36 |
| ▸ | PAICS | P22234 | 1/20 | 0.36 |
| ▸ | GPR6 | P46095 | 3/20 | 0.35 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634835 | 0.94 | PIM1 (0.42) | PIM1TYK2MEN1KMT2ACYP46A1 | |
| SCHEMBL13634676 | 0.86 | GPR6 (0.42) | PIM1PAICSGPR6SMO | |
| SCHEMBL13634801 | 0.85 | CNR1 (0.46) | PIM1IRAK4PAICSGPR6 | |
| SCHEMBL13634596 | 0.85 | GPR6 (0.38) | PIM1PAICSGPR6 | |
| SCHEMBL13634635 | 0.84 | PIM1 (0.45) | PIM1IRAK4GPR6 | |
| SCHEMBL13638871 | 0.84 | TGFBR1 (0.36) | PIM1TYK2PAICSGPR6 | |
| SCHEMBL13634508 | 0.84 | ALDH1A1 (0.41) | PAICSGPR6 | |
| SCHEMBL13634512 | 0.84 | SCD (0.39) | PIM1PIM2PAICSGPR6 | |
| SCHEMBL13634580 | 0.84 | GPR6 (0.36) | PAICSGPR6 | |
| SCHEMBL13634792 | 0.83 | PDE10A (0.46) | PIM1PIM3PIM2IRAK4PAICS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |