Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | GPR6 | P46095 | 8/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.37 |
| ▸ | TNF | P01375 | 2/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | PAICS | P22234 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634791 | 1.00 | PIM1 (0.39) | PIM1GPR6PDE10AP2RX3SCN9A | |
| SCHEMBL13634673 | 0.96 | PIM1 (0.43) | PIM1GPR6P2RX3IRAK4DPP4 | |
| SCHEMBL13634545 | 0.86 | P2RX3 (0.41) | GPR6P2RX3 | |
| SCHEMBL13634546 | 0.85 | GPR6 (0.40) | PIM1GPR6DPP4DPP8DPP9 | |
| SCHEMBL13634777 | 0.82 | P2RX3 (0.44) | GPR6P2RX3 | |
| SCHEMBL13634671 | 0.80 | PDE10A (0.46) | PIM1GPR6PDE10AIRAK4PAICS | |
| SCHEMBL13634792 | 0.80 | PDE10A (0.46) | PIM1GPR6PDE10AIRAK4PAICS | |
| SCHEMBL13634635 | 0.78 | PIM1 (0.45) | PIM1GPR6IRAK4TGFBR1 | |
| SCHEMBL13162688 | 0.78 | P2RX3 (0.42) | P2RX3IRAK4 | |
| SCHEMBL13634623 | 0.77 | PIM1 (0.44) | PIM1GPR6PDE10AIRAK4TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |