Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.41 |
| ▸ | GPR6 | P46095 | 4/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634679 | 0.87 | IRAK4 (0.43) | GPR6IRAK4CHEK1HPGDPDE4D | |
| SCHEMBL13634606 | 0.87 | IRAK4 (0.43) | GPR6IRAK4CHEK1HPGDPDE4D | |
| SCHEMBL13634619 | 0.84 | SCN9A (0.43) | GPR6IRAK4CHEK1HPGDPDE4D | |
| SCHEMBL13634703 | 0.83 | PDE4D (0.42) | GPR6IRAK4CHEK1HPGDPDE4D | |
| SCHEMBL13634648 | 0.83 | MAP3K7 (0.51) | LRRK2GPR6IRAK4CHEK1 | |
| SCHEMBL13638770 | 0.82 | GPR6 (0.42) | GPR6IRAK4CHEK1SCD | |
| SCHEMBL13638935 | 0.80 | SCD (0.44) | GPR6IRAK4CHEK1HPGDSCD | |
| SCHEMBL13634803 | 0.80 | IRAK4 (0.43) | LRRK2IRAK4CHEK1HPGDPDE4D | |
| SCHEMBL13634598 | 0.79 | HRH3 (0.42) | GPR6IRAK4CHEK1SCD | |
| SCHEMBL13634653 | 0.79 | HRH3 (0.41) | GPR6IRAK4CHEK1SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |