Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K7 | O43318 | 8/20 | 0.53 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | TTK | P33981 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634845 | 0.85 | PYGL (0.42) | IRAK4LRRK2 | |
| SCHEMBL13634600 | 0.85 | IRAK4 (0.42) | IRAK4LRRK2 | |
| SCHEMBL13634648 | 0.73 | MAP3K7 (0.51) | MAP3K7IRAK4LRRK2ALKTTK | |
| SCHEMBL13634763 | 0.70 | F10 (0.38) | IRAK4 | |
| SCHEMBL13270429 | 0.70 | IRAK4 (0.38) | MAP3K7IRAK4 | |
| SCHEMBL2774000 | 0.70 | POLB (0.49) | — | |
| SCHEMBL13163173 | 0.69 | GRM2 (0.37) | — | |
| SCHEMBL13634893 | 0.69 | ADORA2A (0.38) | ADORA2AADORA1 | |
| SCHEMBL13270438 | 0.69 | ADORA2A (0.38) | ADORA2AADORA2BADORA1 | |
| SCHEMBL6975265 | 0.68 | LMNA (0.62) | ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |