Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634845 | 0.92 | PYGL (0.42) | IRAK4ALDH1A1KDM4ELMNANPSR1 | |
| SCHEMBL13634688 | 0.85 | MAP3K7 (0.53) | IRAK4LRRK2 | |
| SCHEMBL13634763 | 0.80 | F10 (0.38) | IRAK4ALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL2774000 | 0.80 | POLB (0.49) | ALDH1A1KDM4EPOLBLMNANPSR1 | |
| SCHEMBL13270464 | 0.77 | PTGES (0.37) | IRAK4ALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL13634668 | 0.75 | F10 (0.37) | IRAK4ALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL13270438 | 0.73 | ADORA2A (0.38) | POLB | |
| SCHEMBL18674616 | 0.72 | RAB9A (0.41) | ALDH1A1HPGDKDM4ELMNAHSD17B10 | |
| SCHEMBL3551333 | 0.72 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2A | |
| SCHEMBL13634788 | 0.72 | S1PR1 (0.48) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |