Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14830534 | 0.84 | KMT2A (0.72) | KMT2AMEN1LMNAALDH1A1POLB | |
| SCHEMBL10511025 | 0.84 | KMT2A (0.72) | KMT2AMEN1LMNAALDH1A1POLB | |
| SCHEMBL3462955 | 0.79 | ALDH1A1 (1.00) | KMT2AMEN1ALDH1A1POLBMAPK1 | |
| SCHEMBL457993 | 0.75 | NPC1 (0.84) | KMT2AMEN1LMNAALDH1A1POLB | |
| SCHEMBL29958989 | 0.75 | MEN1 (0.59) | KMT2AMEN1LMNAALDH1A1POLB | |
| SCHEMBL15888637 | 0.75 | NPC1 (0.72) | KMT2AMEN1LMNAALDH1A1POLB | |
| SCHEMBL13164040 | 0.74 | ALDH1A1 (0.60) | KMT2AMEN1LMNAALDH1A1POLB | |
| SCHEMBL13162945 | 0.74 | MEN1 (0.59) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL5969897 | 0.74 | TAS1R3 (0.64) | KMT2AMEN1LMNAALDH1A1HSD17B10 | |
| SCHEMBL18619476 | 0.73 | POLB (0.58) | KMT2AMEN1LMNAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206707-B1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2014-07-23 | — | — | EP | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |