Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 6/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | CYP2J2 | P51589 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GPR6 | P46095 | 4/20 | 0.35 |
| ▸ | PAICS | P22234 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634790 | 0.88 | PIM1 (0.41) | GPR6PAICSCNR1 | |
| SCHEMBL13634821 | 0.82 | GPR6 (0.44) | GPR6PAICSCNR1CNR2 | |
| SCHEMBL13634502 | 0.82 | GPR6 (0.44) | GPR6PAICSCNR1CNR2 | |
| SCHEMBL13634816 | 0.82 | MCHR1 (0.38) | CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL13634745 | 0.81 | BCL3 (0.36) | ALDH1A1 | |
| SCHEMBL13634553 | 0.81 | BCL3 (0.36) | ALDH1A1 | |
| SCHEMBL13634596 | 0.80 | GPR6 (0.38) | CYP2C19KDM4EALDH1A1HPGDGPR6 | |
| SCHEMBL13634500 | 0.78 | GPR6 (0.42) | SCDCYP2C9EPHX2CYP2J2CYP2C19 | |
| SCHEMBL13634676 | 0.78 | GPR6 (0.42) | SCDCYP2C9EPHX2CYP2J2CYP2C19 | |
| SCHEMBL13638871 | 0.78 | TGFBR1 (0.36) | CYP2C9EPHX2CYP2J2CYP2C19GPR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |