Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 7/20 | 0.39 |
| ▸ | RAB9A | P51151 | 7/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7848737 | 0.90 | FPR2 (0.47) | FPR2ALDH1A1HTTMAPK13MAPK12 | |
| SCHEMBL4396673 | 0.76 | FPR2 (0.46) | FPR2ALDH1A1HTTKMT2AMAPT | |
| SCHEMBL7857567 | 0.72 | POLB (0.47) | ALDH1A1HTTKMT2ANPC1RAB9A | |
| SCHEMBL13636880 | 0.70 | EPHX2 (0.43) | FPR2ALDH1A1KMT2AMAPTNPC1 | |
| SCHEMBL22601533 | 0.69 | LMNA (0.71) | ALDH1A1HTTKMT2AFLT3NPC1 | |
| SCHEMBL13636843 | 0.65 | CTDSP1 (0.45) | ALDH1A1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL7858819 | 0.64 | LMNA (0.37) | HTTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL23771955 | 0.64 | NPC1 (0.53) | ALDH1A1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL11972371 | 0.63 | ALDH1A1 (0.61) | FPR2ALDH1A1HTTKMT2AMAPT | |
| SCHEMBL12042421 | 0.63 | NPC1 (0.78) | ALDH1A1KMT2AMAPTFLT3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009132453-A1 | CYCLYLAMINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | NEUROMED PHARMACEUTICALS LTD. (CA) | 2009-11-05 | — | — | WO | disclosed |