Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GRN | P28799 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ESRRA | P11474 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HMGCR | P04035 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25928593 | 0.86 | CA5A (0.38) | CA5ACYP2A6LMNAKDM4EGRN | |
| SCHEMBL6674059 | 0.82 | ALOX15 (0.48) | CA5ALMNAKDM4EGRNSORT1 | |
| SCHEMBL30989545 | 0.80 | CA5A (0.43) | CA5ALMNASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL1204142 | 0.76 | CA5A (0.48) | CA5ALMNAKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL2776048 | 0.76 | GABRA1 (0.50) | CA5ALMNASMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL18307709 | 0.76 | ALDH1A1 (0.43) | LMNAKDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL31085231 | 0.75 | LMNA (0.58) | CYP2A6LMNAKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL10202654 | 0.75 | LMNA (0.58) | CYP2A6LMNAKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL17031818 | 0.75 | ADORA2A (0.51) | KDM4ESMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL17031808 | 0.75 | MEN1 (0.43) | LMNAKDM4ESMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009132453-A1 | CYCLYLAMINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | NEUROMED PHARMACEUTICALS LTD. (CA) | 2009-11-05 | — | — | WO | disclosed |