Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13662235 | 0.91 | KCNH2 (0.40) | JAK2HDAC3HDAC1KCNH2AURKA | |
| SCHEMBL13662231 | 0.91 | KCNH2 (0.40) | JAK2HDAC3HDAC1KCNH2AURKA | |
| SCHEMBL18638718 | 0.91 | NPC1 (0.40) | JAK2CYP1A2NPC1RAB9AMAPT | |
| SCHEMBL13663816 | 0.85 | LDHA (0.38) | JAK2KCNH2NPC1RAB9AMAPT | |
| SCHEMBL13663815 | 0.81 | FTO (0.36) | JAK2KCNH2NPC1RAB9AMAPT | |
| SCHEMBL18266816 | 0.78 | KCNH2 (0.44) | JAK2KCNH2HDAC6ALDH1A1 | |
| SCHEMBL18116829 | 0.78 | KCNH2 (0.44) | JAK2KCNH2MAPTALDH1A1LMNA | |
| SCHEMBL20353098 | 0.77 | KCNH2 (0.44) | JAK2HDAC3HDAC1KCNH2HDAC6 | |
| SCHEMBL25457426 | 0.77 | KCNH2 (0.46) | HDAC3HDAC1KCNH2HDAC6MAPT | |
| SCHEMBL13662234 | 0.76 | KCNH2 (0.43) | KCNH2MAPTSMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009142678-A1 | PROTEIN LABELING WITH CYANOBENZOTHIAZOLE CONJUGATES | PROMEGA CORPORATIN (US) | 2009-11-26 | — | — | WO | disclosed |