Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITPR3 | Q14573 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 2/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13637216 | 0.87 | KCNH2 (0.35) | KCNH2TP53SMN1; SMN2 | |
| SCHEMBL13663814 | 0.84 | NT5E (0.41) | ITPR3KCNH2NT5EFAPMMP14 | |
| SCHEMBL13662233 | 0.78 | NT5E (0.41) | ITPR3KCNH2NT5EMMP14 | |
| SCHEMBL13662226 | 0.76 | KCNH2 (0.43) | ITPR3KCNH2NT5E | |
| SCHEMBL18638159 | 0.76 | — | — | |
| SCHEMBL18806530 | 0.74 | MIF (0.41) | ITPR3KCNH2NT5EFAP | |
| SCHEMBL18116829 | 0.74 | KCNH2 (0.44) | KCNH2NT5E | |
| SCHEMBL18383372 | 0.72 | MIF (0.44) | ITPR3KCNH2FAP | |
| SCHEMBL13662234 | 0.70 | KCNH2 (0.43) | ITPR3KCNH2NT5ETP53SMN1; SMN2 | |
| SCHEMBL18638161 | 0.68 | LMNA (0.36) | KCNH2TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009142678-A1 | PROTEIN LABELING WITH CYANOBENZOTHIAZOLE CONJUGATES | PROMEGA CORPORATIN (US) | 2009-11-26 | — | — | WO | disclosed |