Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | ITPR3 | Q14573 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18383372 | 0.95 | MIF (0.44) | MIFITPR3KCNH2FTOMEN1 | |
| SCHEMBL13663814 | 0.89 | NT5E (0.41) | MIFITPR3KCNH2FTOMEN1 | |
| SCHEMBL13662233 | 0.82 | NT5E (0.41) | MIFITPR3KCNH2FTOMEN1 | |
| SCHEMBL13662226 | 0.80 | KCNH2 (0.43) | MIFITPR3KCNH2MEN1MAPT | |
| SCHEMBL18116829 | 0.78 | KCNH2 (0.44) | MIFKCNH2MEN1MAPTHTT | |
| SCHEMBL19835754 | 0.78 | L3MBTL1 (0.48) | ITPR3KCNH2FTOMEN1MAPT | |
| SCHEMBL19719052 | 0.76 | FTO (0.52) | ITPR3KCNH2FTOMEN1MAPT | |
| SCHEMBL21091701 | 0.76 | FTO (0.45) | ITPR3KCNH2FTOMEN1MAPT | |
| SCHEMBL13637242 | 0.74 | ITPR3 (0.33) | ITPR3KCNH2FAPNT5E | |
| SCHEMBL18638159 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2626703-B1 | Protein labeling with cyanobenzothiazole conjugates | PROMEGA CORP (US) | 2017-05-03 | — | — | EP | disclosed |