Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 10/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634609 | 0.82 | GPR6 (0.41) | GPR6SMN1; SMN2SCDHDAC3HDAC2 | |
| SCHEMBL13634680 | 0.82 | POLB (0.42) | GPR6SCDIRAK4CHEK1 | |
| SCHEMBL13634881 | 0.81 | NPC1 (0.40) | GPR6SMN1; SMN2SCDHDAC3HDAC2 | |
| SCHEMBL13634606 | 0.81 | IRAK4 (0.43) | GPR6SCDIRAK4CHEK1 | |
| SCHEMBL13634679 | 0.81 | IRAK4 (0.43) | GPR6SCDIRAK4CHEK1 | |
| SCHEMBL13634598 | 0.81 | HRH3 (0.42) | GPR6SMN1; SMN2SCDIRAK4HDAC3 | |
| SCHEMBL2770451 | 0.81 | GPR6 (0.43) | GPR6SCDHDAC3HDAC2CHEK1 | |
| SCHEMBL13634653 | 0.81 | HRH3 (0.41) | GPR6SMN1; SMN2SCDIRAK4HDAC3 | |
| SCHEMBL13634849 | 0.80 | GPR6 (0.41) | GPR6SCDHDAC3HDAC2CHEK1 | |
| SCHEMBL13634527 | 0.80 | HRH3 (0.41) | GPR6SCDIRAK4HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |