Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | ARG1 | P05089 | 2/20 | 0.30 |
| ▸ | ARG2 | P78540 | 2/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638748 | 0.86 | ADORA2A (0.35) | SIGMAR1ADORA2AADORA1 | |
| SCHEMBL13638857 | 0.79 | ALDH1A1 (0.47) | ALDH1A1LMNADRD2DRD4DRD3 | |
| SCHEMBL13638957 | 0.75 | HRH3 (0.49) | ALDH1A1LMNA | |
| SCHEMBL13638843 | 0.73 | CCNC (0.37) | — | |
| SCHEMBL20961917 | 0.73 | ALDH1A1 (0.40) | ALDH1A1LMNAMEN1KMT2ACDK1 | |
| SCHEMBL13638859 | 0.72 | HDAC8 (0.51) | ALDH1A1 | |
| SCHEMBL13638752 | 0.71 | GRM2 (0.43) | DRD4 | |
| SCHEMBL13638834 | 0.70 | L3MBTL1 (0.49) | SIGMAR1 | |
| SCHEMBL13638739 | 0.68 | GRM2 (0.42) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL13638876 | 0.68 | DRD4 (0.49) | SIGMAR1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |