Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
| ▸ | TRPC3 | Q13507 | 2/20 | 0.34 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 2/20 | 0.34 |
| ▸ | GPR6 | P46095 | 1/20 | 0.33 |
| ▸ | DCK | P27707 | 2/20 | 0.33 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634327 | 0.81 | DPP4 (0.41) | DPP4DPP9DPP8HRH3AXL | |
| SCHEMBL13162802 | 0.81 | RET (0.41) | HRH3RETPDE3BPDE3APDE10A | |
| SCHEMBL13162320 | 0.80 | NAAA (0.43) | RET | |
| SCHEMBL13634227 | 0.78 | DPP4 (0.44) | DPP4DPP9DPP8DGAT1GPR6 | |
| SCHEMBL13162330 | 0.77 | HRH3 (0.42) | HRH3AXLMERTKCHRM4 | |
| SCHEMBL13162326 | 0.76 | OGA (0.34) | — | |
| SCHEMBL15888604 | 0.76 | DPP4 (0.45) | DPP4DPP9DPP8DGAT1AXL | |
| SCHEMBL13638965 | 0.75 | PDE3B (0.45) | RETPDE3BPDE3APDE10A | |
| SCHEMBL13163989 | 0.74 | CHRM4 (0.34) | AXLMERTKDCKCHRM4 | |
| SCHEMBL13162801 | 0.73 | GPR119 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |