Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.41 |
| ▸ | GPR6 | P46095 | 7/20 | 0.40 |
| ▸ | ITGAL | P20701 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.37 |
| ▸ | PAICS | P22234 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15888604 | 0.87 | DPP4 (0.45) | DPP4DPP9DPP8DGAT1GPR6 | |
| SCHEMBL13634327 | 0.81 | DPP4 (0.41) | DPP4DPP9DPP8IP6K1GPR119 | |
| SCHEMBL13163111 | 0.80 | EPHX2 (0.47) | GPR6 | |
| SCHEMBL13634228 | 0.79 | EPHX2 (0.45) | ACACB | |
| SCHEMBL13638868 | 0.78 | DPP4 (0.38) | DPP4DPP9DPP8DGAT1GPR6 | |
| SCHEMBL13634781 | 0.78 | GPR6 (0.40) | GPR6PAICS | |
| SCHEMBL13634673 | 0.77 | PIM1 (0.43) | DPP4DPP9DPP8GPR6PAICS | |
| SCHEMBL13634229 | 0.76 | HRH3 (0.40) | GPR6KCNH2 | |
| SCHEMBL13634778 | 0.76 | PIM1 (0.39) | DPP4DPP9DPP8GPR6PAICS | |
| SCHEMBL13634791 | 0.76 | PIM1 (0.39) | DPP4DPP9DPP8GPR6PAICS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206707-B1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2014-07-23 | — | — | EP | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |