Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.37 |
| ▸ | LIPC | P11150 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADK | P55263 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.30 |
| ▸ | USP1 | O94782 | 2/20 | 0.30 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634240 | 0.87 | HRH4 (0.33) | PIK3CAMTORHRH4ACACB | |
| SCHEMBL13634239 | 0.86 | AOC3 (0.35) | PIK3CAMTORHRH4ACACB | |
| SCHEMBL13638873 | 0.80 | LIPG (0.46) | LIPGLIPCKMT2AP2RY12ACACB | |
| SCHEMBL15888574 | 0.79 | HCRTR1 (0.42) | LIPGLIPCKMT2AP2RY12 | |
| SCHEMBL13634321 | 0.77 | CHRM3 (0.31) | — | |
| SCHEMBL13634325 | 0.77 | ACACB (0.35) | ACACB | |
| SCHEMBL13634211 | 0.76 | HRH4 (0.39) | HRH4 | |
| SCHEMBL13634326 | 0.76 | GPR119 (0.34) | LIPGHRH4 | |
| SCHEMBL13634313 | 0.75 | CNR2 (0.37) | HRH4P2RY12 | |
| SCHEMBL13634302 | 0.74 | PDE3B (0.47) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |