Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.42 |
| ▸ | MTOR | P42345 | 6/20 | 0.41 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634339 | 0.83 | HTR3A (0.41) | IRAK4PIK3CAMTORHTR3A | |
| SCHEMBL13163110 | 0.80 | PDK1 (0.39) | IRAK4MTORHTR3A | |
| SCHEMBL24375508 | 0.79 | IRAK4 (0.40) | IRAK4PIK3CAMTORPIK3C3PIK3CD | |
| SCHEMBL24375557 | 0.79 | IRAK4 (0.40) | IRAK4PIK3CAMTORPIK3C3PIK3CD | |
| SCHEMBL2079853 | 0.75 | KMO (0.49) | IRAK4PIK3CAPIK3CD | |
| SCHEMBL20594891 | 0.75 | IRAK4 (0.51) | IRAK4PIK3CAMTORPIK3C3 | |
| SCHEMBL10278349 | 0.75 | IRAK4 (0.51) | IRAK4PIK3CAMTORPIK3C3 | |
| SCHEMBL20797900 | 0.74 | ATR (0.44) | PIK3CAMTORPIK3C3PIK3CD | |
| SCHEMBL20797898 | 0.74 | ATR (0.44) | PIK3CAMTORPIK3C3PIK3CD | |
| SCHEMBL29021137 | 0.74 | ATR (0.44) | PIK3CAMTORPIK3C3PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |