Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13639218 | 0.81 | RAB9A (0.49) | ALDH1A1TSHRSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL25062295 | 0.78 | GAA (0.52) | SMN1; SMN2HTTKDM4ETDP1KMT2A | |
| SCHEMBL14199640 | 0.75 | ALDH1A1 (0.51) | ALDH1A1TSHRSMN1; SMN2HTTPOLB | |
| SCHEMBL8882276 | 0.74 | L3MBTL1 (0.57) | TSHRSMN1; SMN2RAB9AKDM4EKMT2A | |
| SCHEMBL25062307 | 0.74 | HTT (0.69) | ALDH1A1TSHRSMN1; SMN2HTTKDM4E | |
| SCHEMBL14200162 | 0.74 | L3MBTL1 (0.47) | TSHRRAB9APOLB | |
| SCHEMBL12299235 | 0.73 | PTGER2 (0.41) | HTTTDP1POLBKMT2A | |
| SCHEMBL12330151 | 0.72 | PTGER2 (0.45) | — | |
| SCHEMBL10504904 | 0.72 | KMT2A (0.48) | ALDH1A1TSHRRAB9AHTTKMT2A | |
| SCHEMBL13946711 | 0.72 | RAB9A (0.55) | ALDH1A1RAB9AKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481976-B1 | 8-AZAPROSTAGLANDIN DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2012-11-07 | — | — | EP | disclosed |
| EP-1603874-B1 | G-LACTAM DERIVATIVES AS PROSTAGLANDIN AGONISTS | SERONO LAB (CH) | 2008-05-07 | — | — | EP | disclosed |