⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7621131 | 0.83 | ALDH1A1 (0.42) | — | |
| SCHEMBL13129853 | 0.78 | — | — | |
| SCHEMBL3103579 | 0.75 | ADRB2 (0.38) | — | |
| SCHEMBL5567339 | 0.75 | — | — | |
| SCHEMBL12518006 | 0.74 | — | — | |
| SCHEMBL7888034 | 0.74 | THRB (0.40) | — | |
| SCHEMBL107911 | 0.74 | — | — | |
| SCHEMBL15765242 | 0.73 | ALDH1A1 (0.37) | — | |
| SCHEMBL2996187 | 0.72 | — | — | |
| SCHEMBL13639460 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231711-B1 | HYDROXYALKYL STARCH DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DE GMBH (DE) | 2012-11-07 | — | — | EP | disclosed |
| WO-2009077154-A1 | HYDROXYALKYL STARCH DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2009-06-25 | — | — | WO | disclosed |
| EP-2070950-A1 | Hydroxyalkyl starch derivatives and process for their preparation | Fresenius Kabi Deutschland GmbH (DE) | 2009-06-17 | — | — | EP | disclosed |