SCHEMBL3103579

SCHEMBL3103579

CCOC(CCON)OCC

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.38
ADRB1 P08588 1/20 0.38
ADRB3 P13945 1/20 0.38
THRB P10828 1/20 0.36
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12997248 0.81 ADRB2 (0.42) ADRB2ADRB1ADRB3THRB
SCHEMBL1701153 0.81 ALDH1A1 (0.39) THRBLMNA
SCHEMBL31079405 0.78 THRB (0.40) THRBLMNA
SCHEMBL5666168 0.76 THRB (0.50) THRBLMNA
SCHEMBL8588639 0.76 THRB (0.38) THRBLMNA
SCHEMBL13639438 0.75
SCHEMBL18042684 0.74 THRB (0.36) THRBLMNA
SCHEMBL15577252 0.74 THRB (0.36) THRBLMNA
SCHEMBL366440 0.72 THRB (0.40) THRBLMNA
SCHEMBL9695937 0.72 THRB (0.40) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130230898-A1 HYDROXYALKYL STARCH DERIVATIVES AND PROCESS FOR THEIR PREPARATION FRESENIUS KABI DEUTSCHLAND GMBH (DE) 2013-09-05 US disclosed
US-20130230898-A1 HYDROXYALKYL STARCH DERIVATIVES AND PROCESS FOR THEIR PREPARATION FRESENIUS KABI DEUTSCHLAND GMBH (DE) 2013-09-05 US disclosed
US-8404834-B2 Hydroxyalkyl starch derivatives and process for their preparation FRESENIUS KABI DEUTSCHLAND GMBH (DE) 2013-03-26 US disclosed
US-8404834-B2 Hydroxyalkyl starch derivatives and process for their preparation FRESENIUS KABI DEUTSCHLAND GMBH (DE) 2013-03-26 US disclosed
US-20100305033-A1 HYDROXYALKYL STARCH DERIVATIVES AND PROCESS FOR THEIR PREPARATION FRESENIUS KABI DEUTSCHLAND GMBH (DE) 2010-12-02 US disclosed
US-20100305033-A1 HYDROXYALKYL STARCH DERIVATIVES AND PROCESS FOR THEIR PREPARATION FRESENIUS KABI DEUTSCHLAND GMBH (DE) 2010-12-02 US disclosed
US-7799913-B2 Carbonylbenzoxazine compounds for enhancing glutamatergic synaptic responses CORTEX PHARMACEUTICALS, INC. (US) 2010-09-21 US disclosed
US-20040259871-A1 Carbonylbenzoxazine compounds for enhancing glutamatergic synaptic responses CORTEX PHARMACEUTICALS, INC 2004-12-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040259871-A1 Carbonylbenzoxazine compounds for enhancing glutamatergic synaptic responses GAP43, GRIN2B, GRIN2A ADRB2 590/4885ADRB1 852/4885ADRB3 979/4885
US-20100305033-A1 HYDROXYALKYL STARCH DERIVATIVES AND PROCESS FOR THEIR PREPARATION HDHD5, KHK, SORD ADRB2 4253/4885ADRB1 3840/4885ADRB3 3536/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.