Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1959777 | 0.72 | TSHR (0.46) | MAPTKMT2ALMNAMEN1RECQL | |
| SCHEMBL28340407 | 0.71 | CYP2D6 (0.41) | MAPTKMT2ALMNARECQL | |
| SCHEMBL9817188 | 0.70 | CYP2C19 (0.41) | CYP2C19KMT2ALMNA | |
| SCHEMBL7403222 | 0.70 | KMT2A (0.41) | MAPTAPAF1KMT2ALMNAMEN1 | |
| SCHEMBL23215107 | 0.69 | KMT2A (0.53) | MAPTAPAF1KMT2ASLC6A3GPR139 | |
| SCHEMBL27838181 | 0.69 | GPR139 (0.49) | MAPTKMT2ALMNAGPR139RECQL | |
| SCHEMBL29664591 | 0.69 | KMT2A (0.53) | MAPTAPAF1KMT2ASLC6A3GPR139 | |
| SCHEMBL10076865 | 0.69 | HPGD (0.44) | MAPTKMT2ALMNARECQLMTNR1A | |
| SCHEMBL3929030 | 0.69 | POLB (0.44) | MAPTKMT2APOLBLMNAMEN1 | |
| SCHEMBL7114570 | 0.67 | PTGS2 (0.47) | MAPTAPAF1KMT2APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948146-B1 | NOVEL MULTI-CYCLIC COMPOUNDS AND THEIR USE | REVOTAR BIOPHARMACEUTICALS AG (DE) | 2012-11-07 | — | — | EP | disclosed |