SCHEMBL3929030

SCHEMBL3929030

CCCC(=O)SC(C)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.44
LMNA P02545 2/20 0.44
ASAH1 Q13510 2/20 0.43
ALDH1A1 P00352 2/20 0.43
ACER2 Q5QJU3 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42
CES2 O00748 2/20 0.42
CES1 P23141 2/20 0.42
MAPT P10636 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
TSHR P16473 1/20 0.40
PAX8 Q06710 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
NAAA Q02083 2/20 0.40
HPGD P15428 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1959777 0.75 TSHR (0.46) LMNACES2CES1MAPTTSHR
SCHEMBL28340407 0.73 CYP2D6 (0.41) LMNACES2CES1MAPTKMT2A
SCHEMBL27838181 0.72 GPR139 (0.49) LMNAALDH1A1NPSR1CES2CES1
SCHEMBL10076865 0.72 HPGD (0.44) LMNACES2CES1MAPTKMT2A
SCHEMBL3633716 0.72 CYP1A2 (0.47) POLBLMNAASAH1ALDH1A1ACER2
SCHEMBL15125811 0.71 POLB (0.49) POLBLMNAALDH1A1NPSR1MAPT
Phenyl Ethanol SCHEMBL17550791 0.70 FFAR3 (0.50) POLBLMNAASAH1ALDH1A1ACER2
SCHEMBL5574869 0.70 ALDH1A1 (0.42) POLBLMNAASAH1ALDH1A1ACER2
SCHEMBL11994163 0.69 HSD11B1 (0.50) LMNAALDH1A1CES2CES1MAPT
SCHEMBL10520485 0.69 CES2 (0.47) LMNAALDH1A1NPSR1CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7585535-B2 Flavour and fragrance compositions GIVAUDAN SA (CH) 2009-09-08 US disclosed
EP-1392132-B1 FLAVOUR AND FRAGRANCE COMPOSITIONS GIVAUDAN SA (CH) 2009-07-29 EP disclosed
CN-1267018-C Flavour and fragrance composition GIVAUDAN SA (CH) 2006-08-02 CN disclosed
US-20040253362-A1 Flavour and fragrance compositions GIVAUDAN SA (CH) 2004-12-16 US disclosed
CN-1512844-A Flavour and fragrance composition ����µ��ɷ����޹�˾ 2004-07-14 CN disclosed
EP-1264547-A1 Flavour and fragrance compositions Givaudan SA (CH) 2002-12-11 EP disclosed