Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | TDO2 | P48775 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12973015 | 0.89 | PTGS2 (0.54) | PTGS2PTGDR2PTGS1ALOX5IDO1 | |
| SCHEMBL7805767 | 0.75 | IDO1 (0.71) | PTGS2PTGDR2PTGS1ALOX5IDO1 | |
| SCHEMBL12973020 | 0.73 | IDO1 (0.42) | PTGS2IDO1TDO2SMN1; SMN2 | |
| SCHEMBL7812894 | 0.72 | IDO1 (0.56) | PTGS2PTGDR2PTGS1ALOX5IDO1 | |
| SCHEMBL7815327 | 0.72 | IDO1 (0.56) | PTGS2PTGDR2PTGS1ALOX5IDO1 | |
| SCHEMBL4241082 | 0.72 | PTGS2 (0.52) | PTGS2PTGDR2TRPM8ALOX5IDO1 | |
| SCHEMBL12973017 | 0.71 | RARA (0.46) | ALOX5IDO1TDO2SMN1; SMN2 | |
| SCHEMBL145807 | 0.71 | LMNA (0.64) | IDO1LMNA | |
| SCHEMBL12973024 | 0.70 | RAB9A (0.45) | PTGS2PTGS1LMNASMN1; SMN2 | |
| SCHEMBL8597621 | 0.70 | IDO1 (0.76) | PTGS2PTGS1ALOX5IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2520572-A1 | Nitrogen-containing fused-ring compound, polymer comprising a nitrogen-containing fused-ring repeating unit, organic thin film, and organic thin film element | SUMITOMO CHEMICAL CO., LTD. (JP) | 2012-11-07 | — | — | EP | disclosed |