SCHEMBL13640189

SCHEMBL13640189

CC1(C)CC(=O)C(=CNc2ccc(N)cc2)C(=O)C1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NTRK3 Q16288 1/20 0.43
▸ NTRK2 Q16620 1/20 0.43
▸ ALDH1A1 P00352 11/20 0.43
▸ MAPT P10636 7/20 0.43
▸ KMT2A Q03164 6/20 0.43
▸ MEN1 O00255 5/20 0.43
▸ KDM4E B2RXH2 3/20 0.43
▸ GAA P10253 3/20 0.43
▸ RECQL P46063 2/20 0.43
▸ TSHR P16473 1/20 0.42
▸ L3MBTL1 Q9Y468 4/20 0.37
▸ CA12 O43570 1/20 0.36
▸ CA1 P00915 1/20 0.36
▸ CA2 P00918 1/20 0.36
▸ CA9 Q16790 1/20 0.36
▸ HIF1A Q16665 1/20 0.36
▸ HPGD P15428 2/20 0.35
▸ PKM P14618 1/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ CYP19A1 P11511 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13640138 0.85 KMT2A (0.49) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL12830161 0.85 ALDH1A1 (0.43) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL13640141 0.84 ALDH1A1 (0.60) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL22057718 0.84 MAOA (0.45) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL8428005 0.84 MAPT (0.51) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL13640144 0.84 ALDH1A1 (0.42) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL11109819 0.83 ALDH1A1 (0.60) ALDH1A1MAPTKMT2AGAATSHR
SCHEMBL12316747 0.81 ALDH1A1 (0.40) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL13640474 0.81 TSHR (0.43) ALDH1A1MAPTKDM4EGAATSHR
SCHEMBL22056817 0.80 L3MBTL1 (0.51) ALDH1A1MAPTKMT2AMEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2477491-B1 PLANT ADDITIVES AND USES THEREOF TO MODULATE THE SYNTHESIS OF MEMBRANE GLYCEROLIPIDS IN PLANTS COMMISSARIAT L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2017-05-17 — — EP disclosed
US-9028855-B2 Plant additives and uses thereof to modulate the synthesis of membrane glycerolipids in planta COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2015-05-12 — — US disclosed
US-9028855-B2 Plant additives and uses thereof to modulate the synthesis of membrane glycerolipids in planta COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2015-05-12 — — US disclosed
US-20120283101-A1 Plant Additives and Uses Thereof to Modulate the Synthesis of Membrane Glycerolipids in Planta COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2012-11-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120283101-A1 Plant Additives and Uses Thereof to Modulate the Synthesis of Membrane Glycerolipids in Planta PGM2, SGMS2, PHOSPHO1 NTRK3 4529/4885NTRK2 4302/4885ALDH1A1 3248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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