Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 5/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | FABP7 | O15540 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.43 |
| ▸ | RNF4 | P78317 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13645022 | 0.91 | CA1 (0.45) | KEAP1NFE2L2PPARGCA1CA2 | |
| SCHEMBL13603876 | 0.87 | ALDH1A1 (0.54) | CA1CA2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL13603920 | 0.83 | ALDH1A1 (0.59) | CA1CA2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL340292 | 0.83 | KEAP1 (0.59) | KEAP1NFE2L2CA1CA2RAB9A | |
| SCHEMBL13681074 | 0.83 | NR3C1 (0.51) | CA1CA2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL13644958 | 0.82 | KEAP1 (0.51) | KEAP1NFE2L2PPARGALDH1A1L3MBTL1 | |
| SCHEMBL13603924 | 0.82 | ALDH1A1 (0.51) | CA1CA2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL6560868 | 0.82 | NR3C1 (0.56) | KEAP1NFE2L2ALDH1A1MAPK1RAB9A | |
| SCHEMBL13603842 | 0.82 | KEAP1 (0.52) | KEAP1NFE2L2PPARGCA1CA2 | |
| SCHEMBL16174068 | 0.81 | PPARG (0.52) | KEAP1NFE2L2PPARGALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090246700-A1 | PLATE-MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR | FUJIFILM CORPORATION (JP) | 2009-10-01 | — | — | US | disclosed |