Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3242043 | 0.81 | ROCK1 (0.53) | ROCK2EIF4E | |
| SCHEMBL12790089 | 0.73 | HPGD (0.69) | HPGDCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10066598 | 0.70 | ENPP2 (0.67) | HPGDENPP2ROCK2HDAC1 | |
| SCHEMBL14368134 | 0.69 | HPGD (0.54) | HPGDCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3240109 | 0.69 | ALDH1A1 (0.58) | HPGDMAPTATMNPSR1L3MBTL1 | |
| SCHEMBL14426771 | 0.66 | IRAK4 (0.69) | MAPTATMGAATLR7RAB9A | |
| SCHEMBL209625 | 0.66 | CYP2D6 (0.54) | HPGDCYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL17175809 | 0.66 | IRAK4 (0.69) | HPGDCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL24499084 | 0.66 | NPC1 (0.49) | HPGDENPP2MAPTATMNPSR1 | |
| SCHEMBL29698296 | 0.66 | NPC1 (0.49) | HPGDENPP2MAPTATMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131952-A1 | COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING THIAZOLE DERIVATIVES | INSTITUTE FOR ONEWORLD HEALTH (US) | 2009-10-29 | — | — | WO | disclosed |