Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Linoleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.69 |
| ▸ | FABP3 | P05413 | 10/20 | 0.96 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | F7 | P08709 | 3/20 | 0.69 |
| ▸ | F3 | P13726 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | PPARG | P37231 | 2/20 | 0.69 |
| ▸ | PPARD | Q03181 | 2/20 | 0.69 |
| ▸ | PPARA | Q07869 | 2/20 | 0.69 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.69 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.69 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.69 |
| ▸ | FABP4 | P15090 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | GNA15 | P30679 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Linoleic Acid SCHEMBL28264278 | 0.98 | FABP3 (0.93) | FABP3ALDH1A1F7F3KDM4E | |
| Linoleic Acid SCHEMBL15022788 | 0.96 | FABP3 (0.96) | FABP3ALDH1A1F7F3KDM4E | |
| Linoleic Acid SCHEMBL2481495 | 0.96 | FABP3 (0.96) | FABP3ALDH1A1F7F3KDM4E | |
| Linoleic Acid SCHEMBL8102953 | 0.96 | FABP3 (0.96) | FABP3ALDH1A1F7F3KDM4E | |
| SCHEMBL25398665 | 0.96 | FABP3 (0.96) | FABP3ALDH1A1F7F3KDM4E | |
| SCHEMBL25400699 | 0.96 | FABP3 (0.96) | FABP3ALDH1A1F7F3KDM4E | |
| Linoleic Acid SCHEMBL10612265 | 0.96 | FABP3 (0.96) | FABP3ALDH1A1F7F3KDM4E | |
| Linoleic Acid SCHEMBL136188 | 0.96 | FABP3 (0.96) | FABP3ALDH1A1F7F3KDM4E | |
| Linoleic Acid SCHEMBL1368595 | 0.96 | FABP3 (0.96) | FABP3ALDH1A1F7F3KDM4E | |
| Linoleic Acid SCHEMBL7638455 | 0.96 | FABP3 (0.96) | FABP3ALDH1A1F7F3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 678 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025118221-A1 | COMPOSITION FOR CLEANSING AND/OR REMOVING MAKEUPS FROM KERATIN MATERIALS | L'OREAL (FR) | 2025-06-12 | — | — | WO | claimed |
| CN-118078649-A | Microcapsules, method for preparing same, and non-cosmetic composition comprising a plurality of microcapsules | 塔格拉生物技术有限公司 | 2024-05-28 | — | — | CN | claimed |
| EP-3784706-B1 | PREPARATION OF AN ACTIVE POLYMER EMULSION | COATEX SAS (FR) | 2024-04-03 | — | — | EP | claimed |
| CN-114456478-B | Antistatic master batch for plastics and plastic film containing same | 山东星达新材料有限公司 | 2024-03-08 | — | — | CN | claimed |
| CN-116474160-A | Injury repair promoting and anti-scar material and preparation method thereof | 山东隽秀生物科技股份有限公司 | 2023-07-25 | — | — | CN | claimed |
| CN-115851102-B | Multi-component soft hand feeling varnish of ABS helmet for electrostatic spraying and preparation method thereof | 雅图高新材料股份有限公司 | 2023-07-11 | — | — | CN | claimed |
| US-20230118672-A1 | SUBSTITUTED POLY(ALKYLENE OXIDE) AND SURFACTANT COMPOSITION | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2023-04-20 | — | — | US | claimed |
| CN-115851102-A | ABS helmet multi-component flexible hand feeling varnish for electrostatic spraying and preparation method thereof | 雅图高新材料股份有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-112028577-B | RPC cover plate for subway evacuation platform and preparation method thereof | 江西龙正科技发展有限公司 | 2023-03-24 | — | — | CN | claimed |
| CN-115583913-B | Zinc burning inhibitor and preparation method and application thereof | 广东工业大学 | 2023-03-17 | — | — | CN | claimed |
| CN-1915045-A | Method for adding polyunsaturated fatty acid in animal milk | FENGXING MILKS CO LTD GUANGZHO (CN) | 2007-02-21 | — | — | CN | claimed |
| CN-1257882-C | Method for synthesizing edible conjugated calcium linoleate | XINJIANG INST OF PHYSICS & CHE (CN) | 2006-05-31 | — | — | CN | claimed |
| CN-1562944-A | Method for synthesizing edible conjugated calcium linoleate | XINJIANG INST OF PHYSICS & CHE (CN) | 2005-01-12 | — | — | CN | claimed |
| EP-0780223-B1 | Multilayered material, method for producing and applications | HUTCHINSON (FR) | 2004-10-27 | — | — | EP | claimed |
| US-20020197229-A1 | Heat-crosslinkable cosmetic composition | L'OREAL (FR) | 2002-12-26 | — | — | US | claimed |
| EP-0319203-A2 | Improvements in materials for the manufacture of fiber-reinforced thermosetting resin mouldings | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-06-07 | — | — | EP | claimed |
| US-4353995-A | TERTIARY AMINE, TIN COMPOUND, AND BARIUM OR CALCIUM CARBOXYLATE | MOBAY CHEMICAL CORPORATION (US) | 1982-10-12 | — | — | US | claimed |
| US-4298003-A | System for delivering agent at zero order rate with emerging agent below saturation | ALZA CORPORATION (US) | 1981-11-03 | — | — | US | claimed |
| EP-0016355-A2 | Novel catalyst system for polyurethane foams and the use thereof | Mobay Chemical Corporation (US) | 1980-10-01 | — | — | EP | claimed |
| US-4217247-A | TERTIARY AMINE, TIN COMPOUND, CALCIUM OR BARIUM CARBOXYLATE | MOBAY CHEMICAL CORPORATION (US) | 1980-08-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230118672-A1 | SUBSTITUTED POLY(ALKYLENE OXIDE) AND SURFACTANT COMPOSITION | DECR2, DECR1, C9 | PTGS1 1134/4885FABP3 3862/4885ALDH1A1 2683/4885 |
| US-20020197229-A1 | Heat-crosslinkable cosmetic composition | KRT18, CUTA, HSPA1B | PTGS1 1767/4885FABP3 3168/4885ALDH1A1 936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.