SCHEMBL1364923

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14094525	0.91	DGAT1 (0.53)	DGAT1KMT2AKDM4EALDH1A1HPGD
	SCHEMBL12141992	0.89	KMT2A (0.51)	KMT2AKDM4EALDH1A1HPGDHSD17B10
	SCHEMBL1367559	0.88	DGAT1 (0.51)	DGAT1ALDH1A1GABRA5CKS1BSKP1
	SCHEMBL12141988	0.88	ATR (0.55)	KMT2AKDM4EALDH1A1HPGDHSD17B10
	SCHEMBL1366388	0.86	POLB (0.63)	KMT2AMAPK1PRKAA1JAK3
	SCHEMBL4406616	0.85	KDM4E (0.58)	KMT2AKDM4EALDH1A1HPGDHSD17B10
	SCHEMBL1364239	0.84	DGAT1 (0.48)	DGAT1KMT2AKDM4EALDH1A1HPGD
	SCHEMBL4636340	0.83	GABRA5 (0.55)	KMT2AATRGABRA5CKS1BSKP1
	SCHEMBL1366822	0.83	DRD4 (0.60)	DGAT1KDM4EALDH1A1MAPK1PRKAA1
	SCHEMBL1366703	0.82	DGAT1 (0.55)	DGAT1GABRA5AXLFLT3TYRO3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.