Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.70 |
| ▸ | HBB | P68871 | 1/20 | 0.70 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.62 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.62 |
| ▸ | NT5E | P21589 | 1/20 | 0.62 |
| ▸ | PYGM | P11217 | 3/20 | 0.55 |
| ▸ | TK2 | O00142 | 2/20 | 0.51 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.49 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15482194 | 1.00 | LMNA (0.70) | LMNASMN1; SMN2TSHRMAPTPMP22 | |
| SCHEMBL13694991 | 1.00 | LMNA (0.70) | LMNASMN1; SMN2TSHRMAPTPMP22 | |
| SCHEMBL26269072 | 0.90 | LMNA (0.60) | LMNASMN1; SMN2TSHRMAPTPMP22 | |
| SCHEMBL6834927 | 0.89 | LMNA (0.69) | LMNASMN1; SMN2TSHRMAPTPMP22 | |
| SCHEMBL26269157 | 0.89 | LMNA (0.58) | LMNASMN1; SMN2TSHRMAPTPMP22 | |
| 5-Fluorouridine SCHEMBL2584234 | 0.88 | PYGM (0.70) | LMNASMN1; SMN2TSHRMAPTPMP22 | |
| 5-Fluorouridine SCHEMBL329747 | 0.88 | PYGM (0.70) | LMNASMN1; SMN2TSHRMAPTPMP22 | |
| 5-Fluorouridine SCHEMBL214536 | 0.88 | PYGM (0.70) | LMNASMN1; SMN2TSHRMAPTPMP22 | |
| 5-Fluorouridine SCHEMBL21423048 | 0.88 | PYGM (0.70) | LMNASMN1; SMN2TSHRMAPTPMP22 | |
| 5-Fluorouridine SCHEMBL53091 | 0.88 | PYGM (0.70) | LMNASMN1; SMN2TSHRMAPTPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598246-B2 | Bisphosphonate conjugates and methods of making and using the same | MBC PHARMA, INC. (US) | 2009-10-06 | — | — | US | disclosed |