Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
| ▸ | PTPRB | P23467 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13657280 | 0.86 | CA2 (0.44) | CA2ESR1HSD11B1ALDH1A1CYP3A4 | |
| SCHEMBL12315287 | 0.82 | PSIP1 (0.59) | CA2ESR1HSD11B1ALDH1A1PSIP1 | |
| SCHEMBL13657278 | 0.82 | ALDH1A1 (0.47) | CA2ESR1HSD11B1ALDH1A1CYP3A4 | |
| SCHEMBL17803840 | 0.81 | ALDH1A1 (0.64) | CA2ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL15577883 | 0.79 | PLCG1 (0.55) | CA2HSD11B1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL2451016 | 0.79 | PSIP1 (0.56) | CA2HSD11B1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL18701019 | 0.79 | ALDH1A1 (0.55) | CA2ESR1HSD11B1ALDH1A1PSIP1 | |
| SCHEMBL2600037 | 0.76 | ESR1 (0.50) | CA2ESR1HSD11B1THRATHRB | |
| SCHEMBL11100709 | 0.75 | ESR1 (0.54) | CA2ESR1HSD11B1ALDH1A1CYP2C9 | |
| SCHEMBL8338766 | 0.75 | CA2 (0.61) | CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090246211-A1 | Molecular constructs suitable for targeted conjugates | TAPESTRY PHARMACEUTICALS, INC. | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090246211-A1 | Molecular constructs suitable for targeted conjugates | MRPL21, QSOX1, MLX | CA2 4114/4885ESR1 1178/4885HSD11B1 3114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.