Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 9/20 | 0.76 |
| ▸ | NR3C1 | P04150 | 9/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.76 |
| ▸ | AR | P10275 | 5/20 | 0.76 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.76 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 6/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | HTR1A | P08908 | 1/20 | 0.67 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2017551 | 0.88 | NR3C1 (0.59) | PGRNR3C1CYP3A4HIF1AAR | |
| Flurandrenolide SCHEMBL5490827 | 0.86 | CYP3A4 (1.00) | PGRNR3C1CYP3A4HIF1AAR | |
| Flurandrenolide SCHEMBL21111542 | 0.86 | CYP3A4 (1.00) | PGRNR3C1CYP3A4HIF1AAR | |
| Flurandrenolide SCHEMBL13769220 | 0.86 | CYP3A4 (1.00) | PGRNR3C1CYP3A4HIF1AAR | |
| Flurandrenolide SCHEMBL5042122 | 0.86 | CYP3A4 (1.00) | PGRNR3C1CYP3A4HIF1AAR | |
| Flurandrenolide SCHEMBL13423594 | 0.86 | CYP3A4 (1.00) | PGRNR3C1CYP3A4HIF1AAR | |
| Flurandrenolide SCHEMBL4694 | 0.86 | CYP3A4 (1.00) | PGRNR3C1CYP3A4HIF1AAR | |
| Flurandrenolide SCHEMBL3692151 | 0.85 | CYP3A4 (0.97) | PGRNR3C1CYP3A4HIF1AAR | |
| SCHEMBL10028415 | 0.83 | PGR (0.85) | PGRNR3C1CYP3A4HIF1AAR | |
| Flunisolide SCHEMBL13026142 | 0.80 | CYP3A4 (1.00) | PGRNR3C1CYP3A4HIF1AAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247488-A1 | ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS | CANNIZZARO CARINA | 2009-10-01 | — | — | US | disclosed |
| US-7432261-B2 | Anti-inflammatory phosphonate compounds | GILEAD SCIENCES, INC. (US) | 2008-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247488-A1 | ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS | PHOSPHO1, TNF, PTGES | PGR 1197/4885NR3C1 310/4885CYP3A4 1894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.