Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 3/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | WNT1 | P04628 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL761339 | 0.80 | ALDH1A1 (0.45) | MKNK1PKMALDH1A1MEN1KMT2A | |
| SCHEMBL22078923 | 0.80 | HDAC8 (0.54) | MKNK1PKMALDH1A1MEN1KMT2A | |
| SCHEMBL26484713 | 0.78 | MKNK1 (0.39) | MKNK1PKMALDH1A1MEN1KMT2A | |
| SCHEMBL4056944 | 0.78 | MKNK1 (0.39) | MKNK1PKMALDH1A1MEN1KMT2A | |
| SCHEMBL13476038 | 0.78 | HDAC8 (0.42) | ALDH1A1MEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL10139268 | 0.78 | — | — | |
| SCHEMBL12849688 | 0.77 | MAPK1 (0.47) | ALDH1A1MEN1KMT2ALMNAGAA | |
| SCHEMBL14010048 | 0.77 | MKNK1 (0.38) | MKNK1PKMALDH1A1MEN1KMT2A | |
| SCHEMBL13783322 | 0.77 | MAPK1 (0.53) | ALDH1A1MEN1KMT2ALMNAGAA | |
| SCHEMBL20159607 | 0.77 | L3MBTL1 (0.51) | ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160054-A1 | IMIDAZOQUINOLINE AMINE DERIVATIVES, PHARMACEUTICAL COMPOSITION, USE THEREOF | CANWELL BIOTECH LIMITED (CN) | 2020-08-06 | — | — | WO | disclosed |
| WO-2017095904-A1 | HETEROBIFUNCTIONAL PAN-SELECTIN ANTAGONISTS HAVING A TRIAZOLE LINKER | GLYCOMIMETICS, INC. (US) | 2017-06-08 | — | — | WO | disclosed |
| EP-1971601-B1 | N4-PHENYL-QUINAZOLINE-4 -AMINE DERIVATIVES AND RELATED COMPOUNDS AS ERBB TYPE I RECEPTOR TYROSINE KINASE INHIBITORS FOR THE TREATMENT OF HYPERPROLIFERATIVE DISEASES | ARRAY BIOPHARMA INC (US) | 2009-10-21 | — | — | EP | disclosed |