Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13655732 | 0.69 | SMN1; SMN2 (0.32) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13655884 | 0.67 | BACE1 (0.35) | MEN1KMT2AALDH1A1LMNAMMP2 | |
| SCHEMBL4062459 | 0.66 | MAPK1 (0.51) | MAPK1MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL14095715 | 0.64 | MAPK1 (0.36) | MAPK1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL27607791 | 0.62 | MAPK1 (0.38) | MAPK1MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL4057796 | 0.62 | MAPK1 (0.43) | MAPK1MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL14345917 | 0.57 | OPRM1 (0.35) | MEN1KMT2A | |
| SCHEMBL13645553 | 0.55 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2350335 | 0.55 | LMNA (0.42) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL11064104 | 0.53 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515724-B1 | MITOTIC KINESIN INHIBITORS | MERCK & CO INC (US) | 2009-10-21 | — | — | EP | disclosed |