SCHEMBL1365697

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1365756	0.90	HPGDS (0.55)	MAP4K4HPGDSGABRA5DRD2DRD4
	SCHEMBL2069960	0.89	HPGDS (0.62)	MAP4K4HPGDSGABRA5GRM5
	SCHEMBL1365108	0.87	MAP4K4 (0.50)	MAP4K4HPGDSGABRA5DRD2DRD4
	SCHEMBL1367638	0.87	USP30 (0.53)	MAP4K4HPGDSGABRA5ADORA2AADORA2B
	SCHEMBL1365112	0.82	MAP4K4 (0.53)	MAP4K4HPGDSGABRA5DRD2DRD4
	SCHEMBL1366021	0.81	DRD2 (0.52)	MAP4K4HPGDSDRD2DRD4GRM5
	SCHEMBL1365691	0.78	MAP4K4 (0.59)	MAP4K4HPGDSGABRA5GRM5
	SCHEMBL347402	0.78	HPGDS (0.50)	HPGDSGABRA5DRD2DRD4HTR7
	SCHEMBL348209	0.78	HPGDS (0.56)	MAP4K4HPGDSGABRA5DRD2DRD4
	SCHEMBL1367288	0.78	PHGDH (0.49)	HPGDSDRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.