Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 7/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | USP2 | O75604 | 2/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 2/20 | 1.00 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dehydrovariabilin SCHEMBL31368572 | 1.00 | MAPT (1.00) | MAPTKDM4ECYP3A4KMT2AMEN1 | |
| SCHEMBL5108163 | 0.82 | MAPT (0.69) | MAPTKDM4ECYP3A4KMT2AMEN1 | |
| SCHEMBL31464865 | 0.75 | KDM4E (0.60) | MAPTKDM4ECYP3A4KMT2AMEN1 | |
| SCHEMBL13891899 | 0.69 | MAPT (0.52) | MAPTKDM4ECYP3A4KMT2AMEN1 | |
| SCHEMBL68899 | 0.69 | MAPT (0.59) | MAPTKDM4ECYP3A4KMT2AMEN1 | |
| SCHEMBL31689707 | 0.69 | MAPT (0.59) | MAPTKDM4ECYP3A4KMT2AMEN1 | |
| SCHEMBL7097279 | 0.69 | KDM4E (0.69) | MAPTKDM4ESMN1; SMN2CYP2D6ALDH1A1 | |
| SCHEMBL3925870 | 0.68 | ESRRB (0.65) | MAPTKDM4ECYP3A4KMT2AMEN1 | |
| SCHEMBL29747120 | 0.68 | MEN1 (0.51) | MAPTKDM4ECYP3A4KMT2AMEN1 | |
| SCHEMBL3144077 | 0.67 | MAPT (0.52) | MAPTKDM4ECYP3A4KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9345694-B2 | Compounds for enhancing arginase activity and methods of using same | CORNELL RESEARCH FOUNDATION, INC. (US) | 2016-05-24 | — | — | US | disclosed |
| US-20130245070-A1 | COMPOUNDS FOR ENHANCING ARGINASE ACTIVITY AND METHODS OF USING SAME | THE RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2013-09-19 | — | — | US | disclosed |
| US-20090253782-A1 | Compounds for Enhancing Arginase Activity and Methods of USe Thereof | CORNELL RESEARCH FOUNDATION, INC. | 2009-10-08 | — | — | US | disclosed |
| US-20090208432-A1 | AH Receptor Antagonists | SYMRISE GMBH & CO., KG (DE) | 2009-08-20 | — | — | US | disclosed |
| US-20090208432-A1 | AH Receptor Antagonists | SYMRISE GMBH & CO., KG (DE) | 2009-08-20 | — | — | US | disclosed |
| WO-2007128725-A1 | 6H-BENZOFURO[3,2-C] [1]BENZOPYRAN AND [2] BENZOPYRANO [4,3-B] [1]BENZOPYRAN DERIVATIVES AND WOOD EXTRACTS OF THESE COMPOUNDS AS ARYL HYDROCARBON RECEPTOR (AHR) ANTAGONISTS FOR THE PREVENTION OF UV-B INDUCED SKIN DAMAGE | SYMRISE GMBH & CO. KG (DE) | 2007-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090208432-A1 | AH Receptor Antagonists | AHR, ARNT, HCAR1 | MAPT 4785/4885KDM4E 2085/4885CYP3A4 337/4885 |
| US-20130245070-A1 | COMPOUNDS FOR ENHANCING ARGINASE ACTIVITY AND METHODS OF USING SAME | ARG2, ARG1, OTC | MAPT 3632/4885KDM4E 1426/4885CYP3A4 3922/4885 |
| US-20090253782-A1 | Compounds for Enhancing Arginase Activity and Methods of USe Thereof | ARG2, ARG1, OTC | MAPT 3726/4885KDM4E 1521/4885CYP3A4 3582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.