Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29424844 | 0.85 | NNMT (0.41) | NNMTSIRT2SIRT1 | |
| SCHEMBL126903 | 0.85 | NNMT (0.41) | NNMTSIRT2SIRT1 | |
| Hydrochloric Acid SCHEMBL3736737 | 0.83 | NNMT (0.40) | NNMTSIRT2SIRT1 | |
| Hydrochloric Acid SCHEMBL30078498 | 0.83 | NNMT (0.40) | NNMTSIRT2SIRT1 | |
| Hydrochloric Acid SCHEMBL3338097 | 0.83 | NNMT (0.40) | NNMTSIRT2SIRT1 | |
| SCHEMBL13657691 | 0.73 | TXNRD1 (0.46) | — | |
| SCHEMBL30271349 | 0.73 | NNMT (0.33) | NNMT | |
| SCHEMBL2955940 | 0.71 | ALDH1A1 (0.42) | — | |
| SCHEMBL31418720 | 0.71 | — | — | |
| SCHEMBL23414839 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090258897-A1 | Substituted benzimidazoles | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258897-A1 | Substituted benzimidazoles | ABCB11, CYP2C19, HRH2 | NNMT 2579/4885SIRT2 1564/4885SIRT1 1445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.