Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPY1R | P25929 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31141108 | 0.75 | ALDH1A1 (0.54) | GAATSHRALDH1A1KCNH2EPHX1 | |
| SCHEMBL13920529 | 0.75 | ALDH1A1 (0.54) | GAAL3MBTL1KDM4ETSHRALDH1A1 | |
| SCHEMBL13920527 | 0.75 | ALDH1A1 (0.54) | GAAL3MBTL1KDM4ETSHRALDH1A1 | |
| SCHEMBL13483586 | 0.74 | MME (0.50) | L3MBTL1KDM4ETSHRALDH1A1CYP3A4 | |
| SCHEMBL2083186 | 0.74 | APAF1 (0.43) | GAATSHRSLC6A4KCNH2CYP3A4 | |
| SCHEMBL2083187 | 0.74 | APAF1 (0.43) | GAATSHRSLC6A4KCNH2CYP3A4 | |
| Hydrochloric Acid SCHEMBL3770055 | 0.74 | GAA (0.51) | GAAL3MBTL1NPY1RSLC6A4KCNH2 | |
| SCHEMBL4291996 | 0.72 | THRB (0.42) | GAAL3MBTL1TSHRALDH1A1LMNA | |
| SCHEMBL12986869 | 0.71 | KCNQ3 (0.51) | GAAL3MBTL1KDM4ETSHRALDH1A1 | |
| SCHEMBL3258696 | 0.71 | SMN1; SMN2 (0.49) | KDM4ETSHRALDH1A1SLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264469-A1 | NOVEL DICARBOXYLIC ACID DERIVATIVES | BIO-PROJET (FR) | 2009-10-22 | — | — | US | disclosed |
| US-20090264469-A1 | NOVEL DICARBOXYLIC ACID DERIVATIVES | BIO-PROJET (FR) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264469-A1 | NOVEL DICARBOXYLIC ACID DERIVATIVES | S1PR2, S1PR1, S1PR5 | GAA 3986/4885L3MBTL1 4812/4885KDM4E 2051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.