SCHEMBL13660329

SCHEMBL13660329

Cc1ccc(C)c2c1CCCC(Br)(Br)C2=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
DRD4 P21917 1/20 0.35
EED O75530 2/20 0.31
SUZ12 Q15022 2/20 0.31
EZH2 Q15910 2/20 0.31
CES2 O00748 2/20 0.31
CES1 P23141 2/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
APAF1 O14727 1/20 0.31
TERT O14746 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
AKR1B1 P15121 1/20 0.31
HPGD P15428 1/20 0.31
ALOX12 P18054 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15747130 0.69 SMN1; SMN2 (0.39) MAOAMAOBAKT1AKT2AKT3
SCHEMBL15747125 0.69 SMN1; SMN2 (0.36) MAOAMAOBAKT1AKT2AKT3
SCHEMBL1274983 0.69 BRD4 (0.47) MAOAMAOBDRD4KDM4EALDH1A1
SCHEMBL29396153 0.69 BRD4 (0.47) MAOAMAOBDRD4KDM4EALDH1A1
SCHEMBL15747124 0.68 SMN1; SMN2 (0.34) MAOAMAOBAKT1AKT2AKT3
SCHEMBL18020326 0.68 SMN1; SMN2 (0.38) KMT2AAKT1AKT2AKT3
SCHEMBL30109390 0.66 KDM4E (0.45) MAOAMAOBDRD4KDM4EALDH1A1
SCHEMBL806442 0.66 KDM4E (0.45) MAOAMAOBDRD4KDM4EALDH1A1
SCHEMBL9040852 0.63 BRD4 (0.48) MAOAMAOBDRD4ALDH1A1LMNA
SCHEMBL18020325 0.62 THRB (0.33) MAOAMAOBMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090263744-A1 ETHYLENICALLY UNSATURATED COMPOUND, LIGHT SENSITIVE COMPOSITION, LIGHT SENSITIVE PLANOGRAPHIC PRINTING PLATE MATERIAL AND PRINTING PROCESS EMPLOYING THE SAME KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2009-10-22 US disclosed
US-20090263744-A1 ETHYLENICALLY UNSATURATED COMPOUND, LIGHT SENSITIVE COMPOSITION, LIGHT SENSITIVE PLANOGRAPHIC PRINTING PLATE MATERIAL AND PRINTING PROCESS EMPLOYING THE SAME KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2009-10-22 US disclosed
US-20090075201-A1 PLANOGRAPHIC PRINTING PLATE MATERIAL, AND CYCLIC UREIDE MOIETY-CONTAINING PHENOLIC RESIN AND ITS SYNTHETIC PROCESS KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2009-03-19 US disclosed
US-20090075201-A1 PLANOGRAPHIC PRINTING PLATE MATERIAL, AND CYCLIC UREIDE MOIETY-CONTAINING PHENOLIC RESIN AND ITS SYNTHETIC PROCESS KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2009-03-19 US disclosed
US-20090042134-A1 Photosensitive composition, photosensitive planographic printing plate material, and image forming method of photosensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC INC. (JP) 2009-02-12 US disclosed
US-20090042134-A1 Photosensitive composition, photosensitive planographic printing plate material, and image forming method of photosensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC INC. (JP) 2009-02-12 US disclosed
US-20080274425-A1 Multilayeer; aluminum support with fluoroalkyl acrylic group containing polymer; alkali soluble resin and an acid generator KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-11-06 US disclosed
US-20080274425-A1 Multilayeer; aluminum support with fluoroalkyl acrylic group containing polymer; alkali soluble resin and an acid generator KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-11-06 US disclosed
US-20080182202-A1 Planographic printing plate material and resin used therein KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-31 US disclosed
US-20080182202-A1 Planographic printing plate material and resin used therein KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-31 US disclosed
US-7192691-B2 Method of manufacturing light sensitive planographic printing plates and method of using the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-03-20 US disclosed
US-7192691-B2 Method of manufacturing light sensitive planographic printing plates and method of using the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-03-20 US disclosed
US-7172851-B2 Light sensitive composition, planographic printing plate material, and image formation method KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-02-06 US disclosed
US-7172851-B2 Light sensitive composition, planographic printing plate material, and image formation method KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-02-06 US disclosed
US-7169535-B2 Photosensitive composition and photosensitive lithographic printing plate KONICA MINOLTA HOLDINGS, INC. (JP) 2007-01-30 US disclosed
US-7169535-B2 Photosensitive composition and photosensitive lithographic printing plate KONICA MINOLTA HOLDINGS, INC. (JP) 2007-01-30 US disclosed
US-20070015086-A1 Photosensitive composition, photosensitive planographic printing plate material, and image forming method of photosensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2007-01-18 US disclosed
US-20070015086-A1 Photosensitive composition, photosensitive planographic printing plate material, and image forming method of photosensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2007-01-18 US disclosed
US-20070009831-A1 PLANOGRAPHIC PRINTING PLATE MATERIAL AND IMAGE FORMATION METHOD KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-01-11 US disclosed
US-20070009831-A1 PLANOGRAPHIC PRINTING PLATE MATERIAL AND IMAGE FORMATION METHOD KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090263744-A1 ETHYLENICALLY UNSATURATED COMPOUND, LIGHT SENSITIVE COMPOSITION, LIGHT SENSITIVE PLANOGRAPHIC PRINTING PLATE MATERIAL AND PRINTING PROCESS EMPLOYING THE SAME ELOVL1, ELOVL6, ELOVL3 MAOA 3071/4885MAOB 2761/4885DRD4 1087/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.