Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1309822 | 0.85 | ALDH1A1 (0.45) | CYP1A2CYP2C19TSHRSLC2A1MAPT | |
| SCHEMBL2625771 | 0.83 | SSTR4 (0.49) | CYP1A2CYP2C19TSHRMAPTHPGD | |
| SCHEMBL2625767 | 0.83 | MAPT (0.51) | TDP1CYP1A2CYP2C19S1PR4MAPT | |
| SCHEMBL9099770 | 0.82 | TDP1 (0.53) | TDP1TSHRS1PR4MAPTHPGD | |
| SCHEMBL30632022 | 0.81 | TSHR (0.50) | TDP1TSHRS1PR4HPGDSMN1; SMN2 | |
| SCHEMBL10649823 | 0.81 | CYP2C19 (0.40) | TDP1CYP1A2CYP2C19TSHRSLC2A1 | |
| SCHEMBL13310617 | 0.81 | S1PR4 (0.44) | CYP1A2CYP2C19SLC2A1S1PR4MRGPRX4 | |
| SCHEMBL21404257 | 0.81 | TSHR (0.50) | TDP1TSHRS1PR4HPGDSMN1; SMN2 | |
| SCHEMBL22000046 | 0.81 | TDP1 (0.51) | TDP1TSHRS1PR4MAPTMRGPRX4 | |
| SCHEMBL18783744 | 0.79 | PKM (0.40) | CYP1A2CYP2C19SLC2A1S1PR4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090258381-A1 | Methods for Determining the Cleavability of Substrates | FORSCHUNGSZENTRUM BORSTEL (DE) | 2009-10-15 | — | — | US | disclosed |
| US-20090104633-A1 | Kit for Highly Sensitive Detection Assays | VYZKUMNY USTAV VETERINARNIHO LEKARSTVI (CZ) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258381-A1 | Methods for Determining the Cleavability of Substrates | CTSF, ADAM17, ADAM10 | TDP1 587/4885CYP1A2 738/4885CYP2C19 786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.