Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 6/20 | 0.65 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.65 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.65 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.65 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.65 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | SRC | P12931 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | MACROD2 | A1Z1Q3 | 1/20 | 0.61 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.61 |
| ▸ | MACROD1 | Q9BQ69 | 1/20 | 0.61 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.61 |
| ▸ | GK | P32189 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12932265 | 0.89 | P2RX3 (0.75) | P2RY1P2RX1P2RX3P2RY2P2RX2 | |
| SCHEMBL25634748 | 0.85 | P2RY1 (0.67) | P2RY1P2RX1P2RX3P2RY2P2RX2 | |
| SCHEMBL13660667 | 0.84 | TGM2 (0.65) | P2RX3P2RY2 | |
| SCHEMBL12932315 | 0.83 | P2RY1 (0.81) | P2RY1P2RX1P2RX3P2RY2P2RX2 | |
| SCHEMBL12884728 | 0.83 | P2RY1 (0.81) | P2RY1P2RX1P2RX3P2RY2P2RX2 | |
| SCHEMBL1062593 | 0.83 | P2RY1 (0.81) | P2RY1P2RX1P2RX3P2RY2P2RX2 | |
| SCHEMBL24063413 | 0.82 | P2RX1 (0.82) | P2RY1P2RX1P2RX3P2RY2P2RX2 | |
| SCHEMBL21082399 | 0.82 | P2RX1 (0.82) | P2RY1P2RX1P2RX3P2RY2P2RX2 | |
| SCHEMBL20820215 | 0.82 | P2RX1 (0.82) | P2RY1P2RX1P2RX3P2RY2P2RX2 | |
| SCHEMBL29642908 | 0.82 | P2RX1 (0.82) | P2RY1P2RX1P2RX3P2RY2P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090258381-A1 | Methods for Determining the Cleavability of Substrates | FORSCHUNGSZENTRUM BORSTEL (DE) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258381-A1 | Methods for Determining the Cleavability of Substrates | CTSF, ADAM17, ADAM10 | P2RY1 4814/4885P2RX1 4549/4885P2RX3 4596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.