Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.79 |
| ▸ | USP2 | O75604 | 6/20 | 0.76 |
| ▸ | ATM | Q13315 | 2/20 | 0.76 |
| ▸ | CFTR | P13569 | 1/20 | 0.76 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.76 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 7/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.37 |
| ▸ | POLB | P06746 | 4/20 | 0.37 |
| ▸ | PLEC | Q15149 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458205 | 0.90 | ABCB1 (0.77) | ABCB1USP2ATMCFTRPAX8 | |
| Hydrochloric Acid SCHEMBL5606345 | 0.89 | USP2 (0.76) | ABCB1USP2ATMCFTRPAX8 | |
| Hydrochloric Acid SCHEMBL29376502 | 0.89 | USP2 (0.76) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL23309754 | 0.89 | ABCB1 (0.76) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL14693687 | 0.89 | ABCB1 (0.76) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL14399387 | 0.88 | ABCB1 (0.78) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL268381 | 0.88 | ABCB1 (1.00) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL9976340 | 0.88 | ABCB1 (0.74) | ABCB1USP2ATMCFTRPAX8 | |
| Hydrochloric Acid SCHEMBL18816029 | 0.87 | USP2 (0.98) | ABCB1USP2ATMCFTRPAX8 | |
| Hydrochloric Acid SCHEMBL29363314 | 0.87 | USP2 (0.98) | ABCB1USP2ATMCFTRPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140357569-A1 | CYCLOSPORIN CONJUGATES | UCL BUSINESS PLC (GB) | 2014-12-04 | — | — | US | disclosed |
| US-20120157385-A1 | CYCLOSPORIN CONJUGATES | UCL BUSINESS PLC (GB) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157385-A1 | CYCLOSPORIN CONJUGATES | CYP11B1, SHMT2, MRM1 | ABCB1 70/4885USP2 4778/4885ATM 4619/4885 |
| US-20140357569-A1 | CYCLOSPORIN CONJUGATES | CYP11B1, SHMT2, MRM1 | ABCB1 68/4885USP2 4774/4885ATM 4515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.