Hydrochloric Acid

Hydrochloric Acid

SCHEMBL29376502

Cl.N=c1ccc2c(-c3ccccc3C(=O)O)c3ccc(N)cc3oc-2c1

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 known ✓ P00918 2/20 0.37
USP2 O75604 5/20 0.76
ATM Q13315 2/20 0.76
CFTR P13569 1/20 0.76
PAX8 Q06710 1/20 0.76
GOPC Q9HD26 1/20 0.76
ABCB1 P08183 1/20 0.76
L3MBTL1 Q9Y468 1/20 0.56
FTO Q9C0B1 2/20 0.45
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
POLB P06746 3/20 0.42
ALPL P05186 1/20 0.42
ALPI P09923 1/20 0.42
ALPG P10696 1/20 0.42
GNG2 P59768 1/20 0.41
GNB1 P62873 1/20 0.41
KDM4E B2RXH2 3/20 0.41
MAPT P10636 2/20 0.41
HPGD P15428 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5606345 1.00 USP2 (0.76) USP2ATMCFTRPAX8GOPC
SCHEMBL458205 0.99 ABCB1 (0.77) USP2ATMCFTRPAX8GOPC
Sulfuric Acid SCHEMBL16593429 0.95 ABCB1 (0.71) USP2ATMCFTRPAX8GOPC
Sulfuric Acid SCHEMBL16593427 0.92 ABCB1 (0.68) USP2ATMCFTRPAX8GOPC
SCHEMBL23309754 0.89 ABCB1 (0.76) USP2ATMCFTRPAX8GOPC
SCHEMBL9979456 0.89 ABCB1 (0.79) USP2ATMCFTRPAX8GOPC
SCHEMBL14693687 0.89 ABCB1 (0.76) USP2ATMCFTRPAX8GOPC
Hydrochloric Acid SCHEMBL18816029 0.87 USP2 (0.98) USP2ATMCFTRPAX8GOPC
Hydrochloric Acid SCHEMBL29363314 0.87 USP2 (0.98) USP2ATMCFTRPAX8GOPC
Hydrochloric Acid SCHEMBL3808879 0.87 USP2 (0.98) USP2ATMCFTRPAX8GOPC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 314 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4624903-A1 LIQUID SPRAY ANALYSIS Rolls-Royce plc (GB) 2025-10-01 EP claimed
US-20250297956-A1 LIQUID SPRAY ANALYSIS ROLLS-ROYCE PLC (GB) 2025-09-25 US claimed
CN-116288357-B Chromogenic corrosive liquid and preparation method and application thereof 湖北亿纬动力有限公司 2024-10-11 CN claimed
CN-116948640-B Method for preparing green light carbon quantum dots with ultrahigh fluorescence quantum yield by one-step hydrothermal method and application 云南大学 2024-09-27 CN claimed
EP-4220164-B1 METHODS AND SYSTEMS FOR QUANTITATIVE IMMUNOHISTOCHEMISTRY VENTANA MED SYST INC (US) 2024-08-21 EP claimed
EP-3391056-B1 CHROMOGENIC PEROXIDASE SUBSTRATES AGILENT TECHNOLOGIES INC (US) 2024-01-17 EP claimed
EP-4056666-B1 ELECTRICAL TERMINAL WITH PASSIVATION LAYER APTIV TECH LTD (BB) 2023-11-01 EP claimed
CN-116948640-A Method for preparing green light carbon quantum dots with ultrahigh fluorescence quantum yield by one-step hydrothermal method and application 云南大学 2023-10-27 CN claimed
CN-116718644-A Carbon dioxide sensor material and device based on ion conduction gain effect 华南师范大学 2023-09-08 CN claimed
US-20230201380-A1 NON-INVASIVE AND LONGITUDINAL MONITORING OF MICROGLIAL ACTIVATION IN RAT BRAIN WITH SUPERMAGNETIC NANOPARTICLE ENHANCED MR IMAGING UNM RAINFOREST INNOVATIONS (US) 2023-06-29 US claimed
CN-116288357-A Chromogenic corrosive liquid and preparation method and application thereof 湖北亿纬动力有限公司 2023-06-23 CN claimed
EP-3555622-B1 METHODS AND SYSTEMS FOR QUANTITATIVE IMMUNOHISTOCHEMISTRY VENTANA MED SYST INC (US) 2023-02-22 EP claimed
EP-4056666-A1 ELECTRICAL TERMINAL WITH PASSIVATION LAYER Aptiv Technologies Limited (BB) 2022-09-14 EP claimed
CN-111072699-B Hydroxyl radical ratio type fluorescent probe and preparation method and application thereof 广州中医药大学(广州中医药研究院) 2022-05-24 CN claimed
EP-3996815-A2 HIV BINDING AGENTS LAUSANNE UNIVERSITY HOSPITAL (CH) 2022-05-18 EP claimed
EP-3980140-A2 LONG-TERM FIRE RETARDANT WITH CORROSION INHIBITORS AND METHODS FOR MAKING AND USING SAME FRS Group, LLC (US) 2022-04-13 EP claimed
US-12636373-B2 Prodrugs with a tridentate self-immolative linker THE GENERAL HOSPITAL CORPORATION (US) 2026-05-26 US disclosed
US-12629555-B2 Long-term fire retardant with magnesium sulfate and corrosion inhibitors and methods for making and using same PERIMETER SOLUTIONS, LP (US) 2026-05-19 US disclosed
WO-2022035805-A1 SUBSTITUTED 1,2,4-OXADIAZOLES AS SMALL MOLECULE INHIBITORS OF UBIQUITIN-SPECIFIC PROTEASE 28 DANA-FARBER CANCER INSTITUTE, INC. (US) 2022-02-17 WO disclosed
US-20220041597-A1 INHIBITING UBIQUITIN SPECIFIC PEPTIDASE 9X FORMA THERAPEUTICS, INC. 2022-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12629555-B2 Long-term fire retardant with magnesium sulfate and corrosion inhibitors and methods for making and using same SLC6A12, SLC9A2, SLC11A2 CA2 13/4885USP2 1230/4885ATM 1067/4885
US-20220041597-A1 INHIBITING UBIQUITIN SPECIFIC PEPTIDASE 9X MCL1, HSPA9, USP10 CA2 4728/4885USP2 147/4885ATM 99/4885
US-12636373-B2 Prodrugs with a tridentate self-immolative linker AURKC, MBOAT7, MBOAT1 CA2 805/4885USP2 1724/4885ATM 385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.