Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.37 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.37 |
| ▸ | UBE2M | P61081 | 1/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664807 | 0.77 | ALDH1A1 (0.45) | MRGPRX4USP2ALDH1A1HPGDUBE2M | |
| SCHEMBL4367428 | 0.75 | AKT1 (0.48) | BACE1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL13665270 | 0.72 | UBE2M (0.38) | MRGPRX4USP2ALDH1A1HPGDUBE2M | |
| SCHEMBL25736670 | 0.70 | HDAC3 (0.53) | BACE1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL7857951 | 0.70 | PSMB5 (0.46) | BACE1ALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL7405554 | 0.70 | HDAC3 (0.55) | BACE1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL20028119 | 0.69 | HDAC3 (0.58) | BACE1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL23288368 | 0.69 | LMNA (0.60) | HDAC3HDAC1HDAC2NCOR2CTSL | |
| SCHEMBL13664693 | 0.68 | ALDH1A1 (0.46) | MRGPRX4USP2ALDH1A1HPGDKDM4E | |
| SCHEMBL8127646 | 0.68 | HDAC1 (0.53) | BACE1HDAC3HDAC1HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |