Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CDK7 | P50613 | 1/20 | 0.37 |
| ▸ | CCNH | P51946 | 1/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13665269 | 0.73 | CYP3A4 (0.39) | CYP3A4KMT2AMEN1LMNAMAPT | |
| SCHEMBL13664858 | 0.70 | KMT2A (0.38) | POLBCYP3A4KMT2AMEN1LMNA | |
| SCHEMBL13664887 | 0.70 | KCNH2 (0.41) | CYP3A4KMT2AMEN1LMNAMAPT | |
| SCHEMBL28009482 | 0.69 | MAPT (0.49) | POLBCYP3A4KMT2AMEN1LMNA | |
| SCHEMBL10779663 | 0.68 | NPC1 (0.41) | POLBKMT2AMEN1LMNAMAPT | |
| SCHEMBL13664860 | 0.67 | MMP8 (0.41) | CYP3A4KMT2AMEN1LMNAMAPT | |
| SCHEMBL1799567 | 0.66 | CYP3A4 (0.53) | POLBCYP3A4KMT2AMEN1LMNA | |
| SCHEMBL11651664 | 0.65 | MEN1 (0.52) | POLBCYP3A4KMT2AMEN1LMNA | |
| SCHEMBL9618277 | 0.65 | CA2 (0.46) | CYP3A4KMT2AMEN1LMNAMAPT | |
| SCHEMBL7442204 | 0.65 | CYP3A4 (0.49) | POLBCYP3A4KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |