Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664688 | 0.70 | KMT2A (0.42) | KMT2AMEN1NPC1RAB9AUSP2 | |
| SCHEMBL13665269 | 0.70 | CYP3A4 (0.39) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL13664855 | 0.70 | POLB (0.40) | KMT2AMEN1NPC1MAPTLMNA | |
| SCHEMBL13664887 | 0.66 | KCNH2 (0.41) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL11651664 | 0.64 | MEN1 (0.52) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL9618277 | 0.64 | CA2 (0.46) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL10779663 | 0.64 | NPC1 (0.41) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL13664860 | 0.63 | MMP8 (0.41) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL20714819 | 0.62 | MAPT (0.50) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL244815 | 0.61 | EPHX1 (0.52) | KMT2AMEN1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |