Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CCR4 | P51679 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664887 | 0.80 | KCNH2 (0.41) | MMP8MMP14CA14CYP3A4LMNA | |
| SCHEMBL13664869 | 0.78 | SIGMAR1 (0.46) | LMNAMEN1KMT2AHTTEPHX2 | |
| SCHEMBL12744490 | 0.73 | ALDH1A1 (0.63) | MMP8MMP14CA14CYP3A4LMNA | |
| SCHEMBL13665269 | 0.72 | CYP3A4 (0.39) | MMP8MMP14CA14CYP3A4LMNA | |
| SCHEMBL11442742 | 0.72 | MMP8 (0.44) | MMP8MMP14CA14CYP3A4LMNA | |
| SCHEMBL735232 | 0.72 | MMP8 (0.50) | MMP8MMP14CA14CYP3A4LMNA | |
| SCHEMBL10888793 | 0.72 | MMP8 (0.46) | MMP8MMP14CA14CYP3A4LMNA | |
| SCHEMBL13664857 | 0.71 | UBE2M (0.41) | MEN1KMT2ACCR4HTTEPHX2 | |
| SCHEMBL9703791 | 0.70 | CYP3A4 (0.53) | MMP8MMP14CA14CYP3A4LMNA | |
| SCHEMBL10887190 | 0.70 | CCR4 (0.47) | MMP8MMP14CA14CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |