SCHEMBL1366692

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12140800	0.98	JAK2 (0.59)	JAK2JAK3JAK1TYK2KCNH2
	SCHEMBL12140778	0.92	JAK2 (0.57)	JAK2JAK3JAK1TYK2KCNH2
	SCHEMBL12140756	0.92	JAK2 (0.57)	JAK2JAK3JAK1TYK2KCNH2
	SCHEMBL14954569	0.90	JAK2 (0.57)	JAK2JAK3JAK1TYK2KCNH2
	SCHEMBL14954571	0.90	JAK2 (0.57)	JAK2JAK3JAK1TYK2KCNH2
	SCHEMBL1368012	0.90	JAK2 (0.55)	JAK2JAK3JAK1TYK2KCNH2
	SCHEMBL1368007	0.90	JAK2 (0.55)	JAK2JAK3JAK1TYK2KCNH2
	SCHEMBL12140794	0.90	JAK2 (0.55)	JAK2JAK3JAK1TYK2KCNH2
	SCHEMBL1365940	0.89	JAK2 (0.56)	JAK2JAK3JAK1TYK2KCNH2
	Hydrochloric Acid SCHEMBL1368475	0.89	JAK2 (0.54)	JAK2JAK3JAK1TYK2KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.